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Analiza transkryptomiczna gruczołów ślinowych komara Anopheles stephensi

Analiza transkryptomiczna gruczołów ślinowych komara Anopheles stephensi

Ana Domingos / Joana Manuel Couto / Renato Silva

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786209556876
68,10 €
IVA incluido
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Malaria ma ogromny wpływ na zdrowie społeczne, dlatego też interakcje między pasożytem malarii a komarem będącym nosicielem tej choroby można wyjaśnić za pomocą różnych metod, w tym transkryptomiki. RNA-seq to nowe podejście, które poprzez porównanie transkryptomu organizmu w różnych warunkach pozwala uzyskać katalog genów o zróżnicowanej ekspresji, stanowiący kluczową informację dla wyboru potencjalnych celów dla szczepionek przeciwko malarii. Potwierdzone metodą qPCR i zestawione z testami wyciszania genów, ostateczna rola tych genów w infekcji może zostać zrozumiana, co prowadzi do poszukiwania nowych celów dla opracowania szczepionek blokujących przenoszenie choroby.

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